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Acarbose is a prescription oral drug that is used to control blood glucosesugarlevels in people type 2 diabetes in conjunction with dietexerciseand other diabetes drugsfor examplemetforminGlucophageor insulinIt belongs to a class of drugs called alpha-glucosidase inhibitorswhich also includes miglitolGlysetCarbohydrates that are eaten are digested by enzymes in the intestine into smaller sugars which are absorbed into the body and increase blood sugar levelsThe process of carbohydrate digestion requires the pancreas to release into the intestine alpha-amylase enzymeswhich digest the large carbohydrates into smaller carbohydrates called oligosaccharidesThe cells lining the small intestine then release alpha-glucosidase enzymes that further digest the oligosaccharides into smaller sugarslike glucosethat can be absorbedAcarbose is a man-made oligosaccharide designed to slow down the actions of alpha-amylase and alpha-glucosidase enzymesthereby slowing the appearance of sugar in the blood after a meal.

Additional adverse events reported from worldwide postmarketing experience include fulminant hepatitis with fatal outcomehypersensitive skin reactionsfor example rasherythemaexanthema and uticariaedemaileus/subileusjaundice and/or hepatitis and associated liver damagethrombocytopeniaand pneumatosis cystoides intestinalissee PRECAUTIONS

Jay WMarksMDis a board-certified internist and gastroenterologistHe graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

Check your blood sugar carefully during a time of stress or illnessif you travelexercise more than usualdrink alcoholor skip mealsThese things can affect your glucose levels and your dose needs may also change.

Intestinal adsorbentsfor examplecharcoaland digestive enzyme preparations containing carbohydrate-splitting enzymesfor exampleamylasepancreatinmay reduce the effect of Precose and should not be taken concomitantly.

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